The Guilford County Solution to the Opioid Problem (GCSTOP) serves residents of Guilford County. The program was initiated through funding provide from the State General Assembly to Guilford County’s Emergency Services for the purpose of addressing the County’s increasing incidence of opioid overdoses and opioid related deaths. The funding is being used to support the development and initial implementation of a Rapid Response Team (RRT) intervention which is designed to prevent repeat overdose and to counsel persistent users to enter treatment or adopt evidence based harm reduction practices. The program serves some of our community’s most vulnerable populations: people who have overdosed and others who are at high risk for opioid related mortality. The program engages these individuals in harm reduction practices, distributes and trains community members and high-risk populations on the use of naloxone, conducts community health education, coordinates community resources with other community partners (such as CURE Triad), operates mobile and fixed-site syringe exchange programs (SEP), and builds relationships focused on ending opioid overdose. The program is administered by UNCG’S Department of Social Work. It leverages ties to many academic units at UNCG that provide technical expertise, medical advice, social and human services capacity, and social science research.